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Thiostrepton, G-Biosciences
SCI_ED

Catalog No. S139831
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Quantity:
1 g
5 g

Description

Thiostrepton is a cyclic peptide antibiotic isolated from Streptomyces azureus. It targets a wide variety of gram-negative and gram-positive bacteria, especially those causing skin infections. It has been used as a marker for selection of recombinant Streptomyces cultures.

Thiostrepton has been shown to inhibit FOXM1, a gene commonly overexpressed in cancer cell lines, thus inhibiting cancer cell growth. Thiostrepton functions by binding elongation factor G (EF-G) and interfering with ribosomal GTPase activity, ultimately inhibiting protein synthesis.

Chemical Identifiers

Molecular Weight (g/mol) 1664.89 g/mol

Specifications

Quantity 1 g
Percent Purity 95%
Grade Molecular Biology
Physical Form Powder
Product Line Gibco
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