Bachem IFN-γ Antagonist, 0.5mg, 158040-83-6, MFCD30475311
Manufacturer: Bachem 4030819.0500
This peptide derived from the ligand binding site of the human γ-interferon (IFN-γ) receptor is an antagonist of human IFN-γ. It inhibited human IFN-γ-induced expression of HLR/DR antigen on Colo 205 cells with an approximate IC₅₀ of 35 µM. Immobilized peptide specifically bound recombinant human IFN-γ (H-1728). Tyrosine substitution at residue 121 allowed facile quantification and conjugation of the peptide.
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