Apexbio Technology LLC Thonzonium Bromide 553-08-2 1g

Supplier:  Apexbio Technology LLC B49621000

Thonzonium Bromide is a surfactant compound identified as an inhibitor of vacuolar ATPase (V-ATPase)-mediated proton transport with an EC50 of approximately 69 M V-ATPase functions as an ATP-dependent proton pump essential for maintaining cellular pH homeostasis by translocating protons across intracellular membranes Investigations show that Thonzonium Bromide disrupts proton translocation without affecting ATP hydrolysis suggesting an uncoupling mechanism of action In cellular studies Thonzonium Bromide reduces cytoplasmic pH levels and inhibits yeast cell growth in a dose-dependent manner It is commonly used as a research tool to study V-ATPase function and to explore cellular processes involving intracellular proton regulation

Catalog No. 50-000-62884