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Cayman Chemical TIe2 InhIbItr 7 500ug
Supplier: Cayman Chemical 19535500 UG
Blocks Tie2 kinase activity (Ki = 1.3 µM), inhibiting angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling (IC50 = 0.3 µM); prevents endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization
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