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Apexbio Technology LLC Timolol Maleate 26921-17-5 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B13505.1
Timolol Maleate (CAS 26921-17-5) is the maleate salt form of the (S)-enantiomer of Timolol a potent non-selective -adrenergic receptor antagonist It exhibits high binding affinity toward both 1 and 2 adrenergic receptor subtypes with reported Ki values of approximately 1 97 nM ( 1) and 2 0 nM ( 2) Timolol maleate functions by competitively blocking adrenergic signaling pathways thus modulating sympathetic nervous system activities It is widely utilized in biomedical research to investigate -adrenergic signal transduction mechanisms and associated physiological processes including cardiac function and ophthalmic conditions
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