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AdipoGen Tirzepatide
Supplier: AdipoGen AGCP30043M025
Chemical. CAS 2023788-19-2. Formula C225H348N48O68. MW 4813.5. Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide GIP and glucagon-like peptide-1 GLP-1 receptor agonist. Tirzepatide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor GIPR or the GLP-1R. Tirzepatide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes T2D, stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner. Tirzepatide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes. Tirzepatide comprises a 39 amino acid linear synthetic peptide conjugated to a C20 fatty diacid moiety through a hydrophilic linker at the lysine residue at position 20.
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