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Cayman Chemical TIrzepatIdesodIum salt 10mg
SDP

Catalog No. 502942003
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A dual GLP-1R and GIP receptor agonist; induces cAMP production in HEK293 cells expressing human GLP-1R or human GIP receptor (EC50s = 6.54 and 1.01 nM, respectively); induces receptor internalization in HEK293 cells expressing human GLP-1R or GIP receptor at 100 nM; decreases body weight, food intake, plasma levels of leptin, triglycerides, and FFAs, hepatic levels of triglycerides, and blood glucose levels in a mouse model of high-fat diet-induced obesity at 10 nmol/kg per day; prevents A. alternata-induced increases in the numbers of eosinophils and lymphocytes levels in the BALF from A. alternata-challenged mice at 50 nmol/kg every three days; inhibits methacholine-induced bronchoconstriction in a mouse model of diabetes-induced asthma at 50 nmol/kg every three days

Catalog No. 50-294-2003 Supplier Cayman Chemical Supplier No. 3974810 MG
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A dual GLP-1R and GIP receptor agonist; induces cAMP production in HEK293 cells expressing human GLP-1R or human GIP receptor (EC50s = 6.54 and 1.01 nM, respectively); induces receptor internalization in HEK293 cells expressing human GLP-1R or GIP receptor at 100 nM; decreases body weight, food intake, plasma levels of leptin, triglycerides, and FFAs, hepatic levels of triglycerides, and blood glucose levels in a mouse model of high-fat diet-induced obesity at 10 nmol/kg per day; prevents A. alternata-induced increases in the numbers of eosinophils and lymphocytes levels in the BALF from A. alternata-challenged mice at 50 nmol/kg every three days; inhibits methacholine-induced bronchoconstriction in a mouse model of diabetes-induced asthma at 50 nmol/kg every three days

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