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Sigma Aldrich Fine Chemicals Biosciences Tissue plasminogen activat1MG

Supplier:  Sigma Aldrich Fine Chemicals Biosciences T08311MG

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Tissue plasminogen activator (tPA) is a protease of the S1 family (trypsin family) and is found in a wide variety of mammalian tissues especially endothelial cells. tPA is secreted as a single chain precursor which is cleaved to a two-chain form by plasmin. Supplied in the single chain form with a molecular weight of ~70nbspkDa. The Tissue Plasminogen Activator (tPA) gene is mapped to human chromosome 8p11.21 and encodes a protease of 69nbspkDa majorly containing serine amino acid residue. It is predominantly expressed in endothelial cells.

Catalog No. 50-291-4345


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