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Medchemexpress LLC Tivantinib | 905854-02-6 | 99.6% | C23H19N3O2 | 100 MG

Supplier: Medchemexpress LLC HY50686100MG
Tivantinib is a highly selective c-Met tyrosine kinase inhibitor, notable for its low molecular weight and as the first orally available selective inhibitor of c-Met. It selectively inhibits c-Met activity in cell-free and cell-based assays, leading to dose-dependent loss of proliferative capacity or caspase-dependent apoptosis in c-Met-expressing cancer cell lines.
- Highly selective c-Met tyrosine kinase inhibitor
- First orally available selective inhibitor of c-Met
- Inhibits c-Met activity in cell-free and cell-based assays
- Induces dose-dependent loss of proliferative capacity or caspase-dependent apoptosis in c-Met-expressing cancer cell lines
- Inhibits human recombinant c-Met with a Ki of approximately 355 nM
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