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Medchemexpress LLC Tk-112690 | 22423-26-3 | 240.21 | 100 G
Supplier: Medchemexpress LLC HYW008491100G
TK-112690 is an inhibitor of UPP1 (uridine phosphorylase 1). It effectively inhibits murine small intestinal uridine phosphorylase (UPase) with an IC50 of 12.5 μM and human small intestinal UPase with an IC50 of 20.0 μM in laboratory settings. The compound has been observed to increase plasma uridine concentration in mice and is utilized for research purposes related to cancer and pulmonary fibrosis.
- Functions as a UPP1 inhibitor.
- Demonstrates in vitro inhibition of murine small intestinal uridine phosphorylase (UPase) with an IC50 of 12.5 μM.
- Exhibits in vitro inhibition of human small intestinal UPase with an IC50 of 20.0 μM.
- Increases plasma uridine concentration in mice.
- Applicable for the study of cancer and pulmonary fibrosis.
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