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Medchemexpress LLC TK-112690 | 22423-26-3 | 240.21 | 500 G

Supplier: Medchemexpress LLC HYW008491500G
TK-112690 is an inhibitor of UPP1 (uridine phosphorylase). It inhibits both murine and human small intestinal uridine phosphorylase. This compound increases plasma uridine concentration in mice and is valuable for research into cancer and pulmonary fibrosis, demonstrating potential in mitigating chemotherapy-induced side effects.
- Inhibits UPP1 (uridine phosphorylase)
- Effective against murine and human small intestinal uridine phosphorylase
- Increases plasma uridine concentration in mice
- Applicable in cancer research
- Applicable in pulmonary fibrosis research
- Mitigates methotrexate-induced weight loss
- Reduces methotrexate-induced mucosal permeability loss
- Reduces pulmonary fibrosis
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