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Medchemexpress LLC TL13-112 | 2229037-19-6 | MFCD12922943 | >98.0% | 1002.6 | C49H60ClN9O10S | 10MG
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Supplier:  Medchemexpress LLC HY12391910MG

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TL13-112 is a PROTAC research compound that targets anaplastic lymphoma kinase (ALK) for proteasomal degradation while inhibiting its kinase activity. It is a bifunctional molecule formed by conjugation of an ALK inhibitor with a cereblon-binding ligand and is used in cellular assays to study target degradation and downstream signaling.

  • Potent ALK inhibition (IC50 = 0.14 nM).
  • Induces degradation of Aurora A, FER, PTK2, and RPS6KA1 in cell assays.
  • Bifunctional PROTAC conjugate of ceritinib and a cereblon-binding pomalidomide ligand.
  • Chemical formula C49H60ClN9O10S; molecular weight ~1002.6 g/mol.
  • Reported analytical purity ≥98% (HPLC).
  • Intended for research use only; not for human or diagnostic applications.

Catalog No. 50-002-38298


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