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Medchemexpress LLC TL8-506 | 1268163-15-0 | 95.0% | 331.37 | 5 MG
Supplier: Medchemexpress LLC HY204575MG
TL8-506 is a specific TLR8 agonist with an EC50 of 30 nM. It has immunomodulatory effects and can be used in the study of tuberculosis and cancer immunotherapy. It can activate dendritic cells, induce pro-inflammatory cytokines, and enhance resistance to *Mycobacterium tuberculosis* infection.
- Specific TLR8 agonist
- Immunomodulatory effects
- Used in tuberculosis research
- Used in cancer immunotherapy research
- Activates dendritic cells in blood and tumors
- Induces secretion of pro-inflammatory cytokines and chemokines
- Promotes activation and recruitment of T cells
- Enhances resistance to *Mycobacterium tuberculosis* infection
- Lowers bacterial load in lungs and livers
- Ameliorates tuberculous pneumonia and alveolitis
- Reduces numbers and area of granulomas
- Increases proportion of central memory CD8+ T cells
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