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Apexbio Technology LLC TMC647055 Choline salt 1204416-97-6 5mg
Supplier: Apexbio Technology LLC B58225
TMC647055 Choline salt (CAS 1204416-97-6) is a small-molecule inhibitor targeting hepatitis C virus (HCV) NS5B polymerase It is designed to inhibit NS5B polymerase activity thereby disrupting viral RNA replication TMC647055 Choline salt exerts its biological activity primarily through non-nucleoside inhibition of NS5B polymerase In cell-based replicon assays utilizing HCV genotype 1b-infected Huh7-Luc cell lines TMC647055 demonstrates inhibitory activity with an IC50 value of 34 nM Based on these pharmacological properties TMC647055 Choline salt holds research potential in studies of HCV polymerase inhibition and viral replication pathways
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