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Medchemexpress LLC TMI-1 (WAY-171318) | 287403-39-8 | 99.6% | 398.50 | C17H22N2O5S2 | 25 MG
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Catalog No. 5000247704
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TMI-1 (WAY-171318) is a small-molecule research inhibitor of TNF-α converting enzyme (TACE/ADAM17) and several matrix metalloproteinases. It shows potent enzymatic activity (reported IC50 ≈ 8.4 nM for TACE), exhibits anti-proliferative and pro-apoptotic effects in cellular models, and modulates inflammatory cytokines such as TNF-α, IL-1β, and IL-6. Identifiers: CAS 287403-39-8; formula C17H22N2O5S2; MW 398.50.

  • High purity (≈99.6%) suitable for research applications.
  • Potent TACE inhibition with reported IC50 ≈ 8.4 nM.
  • Induces apoptosis and inhibits cancer cell proliferation in cell models.
  • Reduces inflammatory cytokine levels in neuronal and inflammatory models.
  • Powder form stable under recommended low-temperature storage.

Catalog No. 50-002-47704 Supplier Medchemexpress LLC Supplier No. HY10144825MG
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TMI-1 (WAY-171318) is a small-molecule research inhibitor of TNF-α converting enzyme (TACE/ADAM17) and several matrix metalloproteinases. It shows potent enzymatic activity (reported IC50 ≈ 8.4 nM for TACE), exhibits anti-proliferative and pro-apoptotic effects in cellular models, and modulates inflammatory cytokines such as TNF-α, IL-1β, and IL-6. Identifiers: CAS 287403-39-8; formula C17H22N2O5S2; MW 398.50.

  • High purity (≈99.6%) suitable for research applications.
  • Potent TACE inhibition with reported IC50 ≈ 8.4 nM.
  • Induces apoptosis and inhibits cancer cell proliferation in cell models.
  • Reduces inflammatory cytokine levels in neuronal and inflammatory models.
  • Powder form stable under recommended low-temperature storage.

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