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Medchemexpress LLC TMP269 | 1314890-29-3 | 98.2% | 514.52 | 200 MG
Supplier: Medchemexpress LLC HY18360200MG
TMP269 is a novel and selective class IIa histone deacetylase (HDAC) inhibitor, targeting HDAC4, HDAC5, HDAC7, and HDAC9. It is intended for research use only. TMP269 modulates cell cycle progression and enhances cytotoxicity in certain cell lines, without affecting class I or IIb HDACs. It has also shown antiangiogenic effects in vivo.
- Novel and selective class IIa histone deacetylase (HDAC) inhibitor
- Targets HDAC4, HDAC5, HDAC7, and HDAC9
- Modulates cell cycle progression in IEC-18 intestinal epithelial cells
- Enhances CFZ-induced cytotoxicity in MM cell lines
- No inhibitory effects on class I or IIb HDACs
- Demonstrates antiangiogenic effects in vivo
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