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Cayman Chemical TndospIron 50mg
Supplier: Cayman Chemical 4043650 MG
A 5-HT1A partial agonist; selectively binds to 5-HT1A receptors (Ki = 0.027 µM) over 5-HT2, 5-HT1B, 5-HT1C, and 5-HT1D receptors (Kis = 1.3, >100, 2.6, and >100 µM, respectively), as well as α1-ARs, α2-ARs, β-ARs, and dopamine D1 and D2 receptors (Kis = 1.6, 1.9, >100, 1.7, and 41 µM, respectively); reduces forskolin-induced adenylate cyclase activity in rat hippocampal homogenates from 0.1-100 µM; reduces immobility time in the forced swim test in mice at 10 and 20 mg/kg; increases food intake and overall survival, as well as decreases body weight loss in a Yoshida hepatoma rat model of cancer cachexia
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