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Medchemexpress LLC Tnf-α-in-2 | 2074702-04-6 | MFCD34471028 | 99.2% | C25H21ClF2N6O | 10MG
SDP

Supplier:  Medchemexpress LLC HY13447110MG

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TNF-α-IN-2 is a small-molecule, orally active inhibitor of tumor necrosis factor alpha for research applications. It distorts the TNFα trimer to alter signaling and reduces E-selectin expression in cellular assays.

  • Potent TNFα inhibition with HTRF IC50 of 25 nM.
  • Inhibits E-selectin expression in HUVECs (IC50 30 nM).
  • High purity: 99.2%.
  • Solid, light yellow to yellow appearance.
  • Soluble in DMSO (100 mg/mL; may require sonication).
  • Stable as powder at -20 °C for long-term storage.
  • Available in multiple milligram pack sizes for research use only.

Catalog No. 50-002-60214


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