Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Genscript Corporation Antibody Protein Proteins Proteins 50 UG 1/EA
Supplier: Genscript Corporation Z0310450
TNF Receptor Type I is also known as TNF R-p55/p60 and TNFRSF1A. It is a type I transmembrane protein member of the TNF receptor superfamily. It is expressed in most cell types. Binding of either TNF-Alpha or TNF-beta to TNF-R1 initiates a signal transduction pathway that results in the activation of the transcription factor NF-κB whose target genes are involved in the regulation of inflammatory responses and in certain cells induce apoptosis. TNF-R1 is essential for proper development of lymph node germinal centers and Peyers patches and for combating intracellular pathogens such as Listeria. It is stored in the Golgi and translocates to the cell surface following proinflammatory stimuli.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?