Tobramycin sulfate

Description

A water-soluble aminoglycoside antibiotic | CAS: 49842-07-1 | C18H39N5O13S | 565.59 g/mol

Tobramycin sulfate is used as an antibiotic which is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It is used to inhibit bacterial protein synthesis at the level of 30S (16S rRNA) and 70S ribosomal complex assembly. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis and other soft-tissue infections. It is a potential therapy for sinus infections1. Product T1783 has been used to study antibiotic resistance2.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tobramycin sulfate is used as an antibiotic which is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It is used to inhibit bacterial protein synthesis at the level of 30S (16S rRNA) and 70S ribosomal complex assembly. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis and other soft-tissue infections. It is a potential therapy for sinus infections1. Product T1783 has been used to study antibiotic resistance2.

Solubility
Soluble in water (50 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specifications

Chemical Identifiers

• CAS: 49842-07-1
• Molecular Formula: C18H39N5O13S
• Molecular Weight (g/mol): 565.59
• MDL Number: MFCD00133864,MFCD00133864
• InChI Key: ZEUUPKVZFKBXPW-UHFFFAOYNA-N
• PubChem CID: 54413
• IUPAC Name: 4-amino-2-[(4,6-diamino-3-{[3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl)oxy]-6-(hydroxymethyl)oxane-3,5-diol; sulfuric acid
• SMILES: OS(O)(=O)=O.NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O

• Type: Tobramycin Sulfate
• Physical Form: Powder
• Color: White
• Quantity: 100 mg
• Merck Index: 14,9490
• Solubility Information: Soluble in water (50mg/ml).
• Formula Weight: 1425.41
• Chemical Name or Material: Tobramycin sulfate

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
RTECSNumber	WK2110000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only