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Tocris Bioscience™ BAM (8-22)
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Catalog No. 17631
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17-631 1 mg
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Catalog No. 17-631 Supplier Tocris Bioscience™ Supplier No. 1763/1
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Description

Potent MRGPRX1 agonist

BAM (8-22) is an endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM). It was first isolated from bovine adrenal medulla. Unlike BAM 22P (Cat. No. 1650), BAM (8-22) does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors. BAM (8-22) augments scratching behavior in a cholestatic pruritus mice model. BAM (8-22) attenuates bone cancer pain in mice.

Specifications

Purity 0.95
Common Name Mas-Related G Protein Coupled Receptor Agonists
Content And Storage Store at -20°C
Quantity 1 mg
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