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Tocris Bioscience™ COG 133
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Catalog No. 34051
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

ApoE peptide fragment

COG 133 is an apolipoprotein (ApoE) peptide fragment that functions via the low-density lipoprotein receptor-related protein (LRP). Substantially reduces the symptoms of experimental autoimmune encephalomyelitis, a model of human multiple sclerosis, and suppresses inflammation, demyelination and infiltration of cells into the spinal cord. Also acts as a non-competitive antagonist at α7 nicotinic acetylcholine receptors (IC50 = 445 nM).

Specifications

Purity 95%
Quantity 1 mg
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