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Tocris Bioscience™ MOG (35-55)
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Catalog No. 25681
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25-681 1 mg
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Catalog No. 25-681 Supplier Tocris Bioscience™ Supplier No. 2568/1
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Description

Encephalitogenic myelin oligodendrocyte glycoprotein fragment

MOG (35-55) or myelin oligodendrocyte glycoprotein (MOG) 35-55 is a minor component of CNS myelin. MOG (35-55) produces a relapsing-remitting neurological disease with extensive plaque-like demyelination, common to the manifestations of multiple sclerosis. MOG (35-55) induces strong T and B cell responses and is highly encephalitogenic. MOG (35-55) induces T cell-mediated multiple sclerosis in animal models. When co-administered with ITE, MOG (35-55) induces tolerogenic dendritic cells and suppresses disease development in mouse preclinical models of multiple sclerosis.

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