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Cayman Chemical Tol-LIke Receptr 7 LIgnd I 1mg

Supplier: Cayman Chemical 172281 MG

An orally active selective inhibitor of Cdk4 (IC50 11 nM) and Cdk6 (IC50 16 nM) with antiproliferative activity against retinoblastoma-positive tumor cells blocking retinoblastoma phosphorylation and inducing G1 arrest used to demonstrate a role for insulin-activated cyclin D1-Cdk4 signaling in the control of glucose metabolism
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