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Medchemexpress LLC Tolazamide | 1156-19-0 | MFCD00083504 | 99.9% | 100 MG
SDP

Supplier:  Medchemexpress LLC HYB0920100MG

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Tolazamide (U-17835) is an orally active sulfonylurea agent that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (IC50 = 4.2 μM in HEK293 cells transfected with the human receptor). It possesses anti-diabetic properties, lowering blood glucose in the sulfonylurea class. Tolazamide decreases insulin dose while maintaining adequate metabolic control and can improve or normalize hyperglycemia and HbA.

  • Orally active sulfonylurea agent
  • Inhibits sulfonylurea receptor 1 (SUR1)
  • Lowers blood glucose
  • Decreases insulin dose while maintaining metabolic control
  • Improves or normalizes hyperglycemia and HbA
  • Attenuates gluconeogenesis and ketogenesis in diabetic rats

Catalog No. 50-004-08710


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