Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Tolinapant | 1799328-86-1 | 99.81% | 539.68 | 10 MG
Supplier: Medchemexpress LLC HY109565100MG
Tolinapant is an orally bioavailable dual antagonist of cellular inhibitor of apoptosis protein (cIAP) and X-linked inhibitor of apoptosis protein (XIAP). It is for research use only.
- Being investigated in a single-agent Phase 1/2 clinical trial for advanced solid tumors and lymphomas.
- Demonstrated sensitivity in 43% of cell lines treated in vitro.
- Induces moderate tumor growth inhibition in HCC1806 xenografts in mice with daily oral treatment.
- High solubility: 100 mg/mL (185.29 mM) in DMSO.
- Solubility in mixed solvents is ≥ 2.5 mg/mL (4.63 mM), forming clear solutions.
- Stable for extended periods: 3 years as powder at -20°C, 2 years as powder at 4°C, 2 years in solvent at -80°C, and 1 year in solvent at -20°C.
- Targets IAP and Apoptosis pathways.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?