Tolmetin sodium salt dihydrate, 98+%

Description

An NSAID compound | CAS: 64490-92-2 | C15H18NNaO5 | 315.301 g/mol

Tolmetin Sodium is an anti-inflammatory, antirheumatic agent. It can inhibit aldo-keto reductases (e.g., IC50 = 2.39 μM for human aldose reductase), a family of enzymes that catalyze the NADPH-dependent reduction of carbonyl groups in a number of important steroid, metabolic, and prostanoid molecules. It is a beta-adrenergic blocker.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tolmetin Sodium is an anti-inflammatory, antirheumatic agent. It can inhibit aldo-keto reductases (e.g., IC50 = 2.39 µM for human aldose reductase), a family of enzymes that catalyze the NADPH-dependent reduction of carbonyl groups in a number of important steroid, metabolic, and prostanoid molecules. It is a beta-adrenergic blocker.

Solubility
Soluble in water

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 64490-92-2
• Molecular Formula: C15H18NNaO5
• Molecular Weight (g/mol): 315.301
• MDL Number: MFCD00150761
• InChI Key: QQILXENAYPUNEA-UHFFFAOYSA-M
• Synonym: tolmetin sodium dihydrate, sodium tolmetin dihydrate, tolumetin sodium dihydrate, unii-02n1tzf99f, sodium 2-1-methyl-5-4-methylbenzoyl-1h-pyrrol-2-yl acetate dihydrate, tolmetin sodium salt dihydrate, sodium 1-methyl-5-p-toluoylpyrrole-2-acetate dihydrate, tolectin tn, 1-methyl-5-p-toluoyl pyrrole-2 acetic acid
• PubChem CID: 23677829
• ChEBI: CHEBI:72014
• IUPAC Name: sodium;2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetate;dihydrate
• SMILES: CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)[O-].O.O.[Na+]

• Color: White
• Quantity: 25 g
• Merck Index: 14,9518
• Solubility Information: Soluble in water
• Formula Weight: 315.30 (279.27 Anhydrous)
• Percent Purity: ≥98%
• Physical Form: Powder
• Chemical Name or Material: Tolmetin sodium salt dihydrate

Safety and Handling

Hazard Category	H302-H315-H319
Hazard Statement	GHS H Statement H302-H315 Harmful if swallowed. Causes skin irritation.
Precautionary Statement	P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P362-P501c
EINECSNumber	252-687-3
RTECSNumber	UX9280000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only