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Tolnaftate

Catalog No. AAJ6183403
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Catalog No. AAJ6183403 Supplier Thermo Scientific Chemicals Supplier No. J6183403
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Description

Antifungal agent | CAS: 2398-96-1 | C19H17NOS | 307.411 g/mol

Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete?s foot, jock itch, and ringworm1. It also has been used as a comparator compound for antifungal efficiency studies.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 2398-96-1
Molecular Formula C19H17NOS
Molecular Weight (g/mol) 307.411
MDL Number MFCD00056611
InChI Key FUSNMLFNXJSCDI-UHFFFAOYSA-N
Synonym Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester; Carbamothioic acid
PubChem CID 5510
ChEBI CHEBI:9620
IUPAC Name O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate
SMILES CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2

Specifications

Type Tolnaftate
Physical Form Powder
Melting Point 110°C to 113°C
Color White
Quantity 1 g
Merck Index 14,9519
Solubility Information Soluble in chloroform at 50 mg/ml; Sparingly soluble in ethanol or methanol
Formula Weight 307.41
Chemical Name or Material Tolnaftate

Safety and Handling

EINECSNumber 219-266-6
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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