Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502990059

Cayman Chemical ToltrazurIl sulfon 100mg
SDP

Supplier:  Cayman Chemical 29655100 MG

Encompass_Preferred

An inhibitor of STAT3 binds to STAT3 (Kd 504 nM) and inhibits STAT3 binding to an IL-6R/gp130 peptide in a fluorescence polarization assay (IC50 4 1 UM) decreases viability and proliferation of STAT3-dependent NIH3T3/v-Src MDA-MB-231 PANC-1 DU145 and A549 cancer cells but not STAT3-independent NIH3T3 NIH3T3/vRas TE-71 and A2780S cancer cells at 10-30 UM reduces tumor growth and inhibits expression of the STAT3-dependent genes encoding c-Myc survivin Bcl-xL cyclin D1 and VEGF in MDA-MB-231 and A549 mouse xenograft models at 1 and 3 mg/kg

Catalog No. 50-299-0059


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.