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Medchemexpress LLC Toltrazuril (sulfone) | 69004-04-2 | 98.6% | 457.38 | 1 G

Supplier: Medchemexpress LLC HY170081G
Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril that exhibits antiprotozoal activity. It is a triazine anticoccidial developed for the prevention of coccidiosis in poultry. The product is for research use only and not for sale to patients.
- Antiprotozoal activity.
- Metabolite of Toltrazuril.
- Triazine anticoccidial.
- Developed to prevent coccidiosis in poultry.
- Inhibits the development of merozoites of *S. neurona* *in vitro*.
- Inhibits the development of *N. caninum* *in vitro* after approximately 48 hours post-exposure.
- Exhibits inhibitory effects possibly by targeting different enzyme/enzyme systems in various apicomplexans.
- Inhibits *T. gondii* replication *in vitro* after the second division by endodyogeny.
- Effective *in vivo* in preventing and treating toxoplasmosis in mice at dosages of 10-20 mg/kg (p.o.; daily; for 10 days).
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