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Cayman Chemical TomatIdInhydrochlorIde 100mg

Supplier: Cayman Chemical 16938100 MG
A steroidal alkaloid with diverse biological activities; suppresses NF-κB signaling as well as iNOS and COX-2 expression in LPS-stimulated macrophages; inhibits acid sphingomyelinase activity at 10 mM; preferentially blocks replication of S. aureus variants that are pathogenic in cystic fibrosis over normal strains (MICs = 0.12 and >16 UG/ml, respectively); prevents skeletal muscle atrophy associated with fasting or spinal cord injury in mice; has been used as a negative control for cyclopamine in studies involving signaling mediated by the hedgehog pathway
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