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Medchemexpress LLC HY-100022 1mg Medchemexpress, Tomivosertib CAS:1849590-01-7 Purity:>98%
Supplier: Medchemexpress LLC HY1000221MG
Medchemexpress, HY-100022 1mg Tomivosertib CAS:1849590-01-7 Tomivosertib (eFT508) is a potent, highly selective, and orally active MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms. Tomivosertib (eFT508) treatment leads to a dose-dependent reduction in eIF4E phosphorylation at serine 209 (IC50=2-16 nM) in tumor cell lines. Tomivosertib (eFT508) also dramatically downregulates PD-L1 protein abundance[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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