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Medchemexpress LLC Topiramate (Standard) | 97240-79-4 | 99.8% | 10 MM * 1 ML
Supplier: Medchemexpress LLC HYB012210MM/1ML
Topiramate is a broad-spectrum antiepileptic agent and a GluR5 receptor antagonist. Its antiepileptic effects are attributed to enhancing GABAergic activity, inhibiting kainate/AMPA receptors, blocking voltage-sensitive sodium and calcium channels, increasing potassium conductance, and inhibiting carbonic anhydrase.
- Enhances GABAergic activity
- Inhibits kainate/AMPA receptors
- Blocks voltage-sensitive sodium and calcium channels
- Increases potassium conductance
- Inhibits carbonic anhydrase
- Use-dependent inhibition of voltage-dependent Na+ channels in neurons
- Potentiation of GABA (γ-amino-butyric acid)-induced Cl- influx
- Antagonizes kainate/AMPA receptors for inhibitory effects on inward currents
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