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Medchemexpress LLC Topiramate (Standard) | 97240-79-4 | 99.8% | 10 MM * 1 ML
SDP

Catalog No. 5000450752
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Topiramate is a broad-spectrum antiepileptic agent and a GluR5 receptor antagonist. Its antiepileptic effects are attributed to enhancing GABAergic activity, inhibiting kainate/AMPA receptors, blocking voltage-sensitive sodium and calcium channels, increasing potassium conductance, and inhibiting carbonic anhydrase.

  • Enhances GABAergic activity
  • Inhibits kainate/AMPA receptors
  • Blocks voltage-sensitive sodium and calcium channels
  • Increases potassium conductance
  • Inhibits carbonic anhydrase
  • Use-dependent inhibition of voltage-dependent Na+ channels in neurons
  • Potentiation of GABA (γ-amino-butyric acid)-induced Cl- influx
  • Antagonizes kainate/AMPA receptors for inhibitory effects on inward currents

Catalog No. 50-004-50752 Supplier Medchemexpress LLC Supplier No. HYB012210MM/1ML
May include imposed supplier surcharges.
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Topiramate is a broad-spectrum antiepileptic agent and a GluR5 receptor antagonist. Its antiepileptic effects are attributed to enhancing GABAergic activity, inhibiting kainate/AMPA receptors, blocking voltage-sensitive sodium and calcium channels, increasing potassium conductance, and inhibiting carbonic anhydrase.

  • Enhances GABAergic activity
  • Inhibits kainate/AMPA receptors
  • Blocks voltage-sensitive sodium and calcium channels
  • Increases potassium conductance
  • Inhibits carbonic anhydrase
  • Use-dependent inhibition of voltage-dependent Na+ channels in neurons
  • Potentiation of GABA (γ-amino-butyric acid)-induced Cl- influx
  • Antagonizes kainate/AMPA receptors for inhibitory effects on inward currents

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