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Medchemexpress LLC Topoisomerase I inhibitor 8 | 210346-40-0 | 99.9% | 420.43 | 5 MG
SDP

Catalog No. 5000362801
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Topoisomerase I inhibitor 8 is a potent topoisomerase I inhibitor and a hexacyclic analogue of camptothecin. It demonstrates cytotoxic effects against tumor cells.

  • Potent topoisomerase I inhibitor
  • Hexacyclic analogue of camptothecin
  • Displays cytotoxic effects against tumor cells
  • Inhibits murine leukemia cells (P388) with an IC50 of 0.22 ng/mL
  • Inhibits human lung cancer cells (QG-56) with an IC50 of 0.17 ng/mL
  • Shows stronger effectiveness than SN-38 in changing DNA from supercoiled to relaxed form
  • Appears as a light yellow to brown solid
  • Soluble in DMSO at 50 mg/mL

Catalog No. 50-003-62801 Supplier Medchemexpress LLC Supplier No. HY1480585MG
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Topoisomerase I inhibitor 8 is a potent topoisomerase I inhibitor and a hexacyclic analogue of camptothecin. It demonstrates cytotoxic effects against tumor cells.

  • Potent topoisomerase I inhibitor
  • Hexacyclic analogue of camptothecin
  • Displays cytotoxic effects against tumor cells
  • Inhibits murine leukemia cells (P388) with an IC50 of 0.22 ng/mL
  • Inhibits human lung cancer cells (QG-56) with an IC50 of 0.17 ng/mL
  • Shows stronger effectiveness than SN-38 in changing DNA from supercoiled to relaxed form
  • Appears as a light yellow to brown solid
  • Soluble in DMSO at 50 mg/mL

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