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Abcam Torin 1, mTOR inhibitor, 25MG
Supplier: Abcam AB21860625MG
MW 607.6 Da, Purity >98%. Potent, selective, ATP-competitive mTOR inhibitor that directly inhibits both mTORC1 and mTORC2 complexes, with IC₅₀ values between 2 and 10 nM in in vitro kinase assays. Displays 1000-fold selectivity for mTOR over PI3K, 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34, and exhibits 100-fold binding selectivity relative to 450 other protein kinases. Impairs cell growth and proliferation.
The product is subject to the following: Abcam Restricted Use Statement
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