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Medchemexpress LLC Tos-PEG5-CH2COOtBu | 1949793-62-7 | MFCD30828689 | ≥95% | C23H38O10S | 100 MG
Supplier: Medchemexpress LLC HY140366100MG
Tos-PEG5-CH2COOtBu is a PEG linker that contains a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media, and the t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group serves as an excellent leaving group for nucleophilic substitution reactions. This compound is a PEG-based PROTAC linker used in the synthesis of PROTACs.
- Contains a t-butyl ester and a tosyl group.
- Hydrophilic PEG spacer enhances solubility in aqueous media.
- T-butyl protected carboxyl group can be deprotected under acidic conditions.
- Tosyl group serves as a leaving group for nucleophilic substitution reactions.
- Used as a PEG-based PROTAC linker in PROTAC synthesis.
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