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Apexbio Technology LLC Tosyllysine Chloromethyl Ketone (hydrochloride) 4272-74-6 250mg
Supplier: Apexbio Technology LLC C5839250
Tosyllysine Chloromethyl Ketone hydrochloride is a small-molecule inhibitor of serine proteases with trypsin-like activity acting through irreversible covalent modification of protease active sites It can also inhibit certain cysteine proteases and thiol-dependent enzymes via nonspecific reactivity with free thiols In cell-based assays it suppresses inducible nitric oxide synthase (iNOS) expression in stimulated macrophages and modulates protease-mediated cytotoxicity induced by bacterial factors These properties highlight its research value in protein extraction and purification regulation of cellular proteolysis and studies of protease-dependent cellular responses
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