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Apexbio Technology LLC Tozadenant 870070-55-6 250mg

Supplier: Apexbio Technology LLC A3885250
Tozadenant is a small-molecule antagonist targeting the adenosine A2A receptor It is designed to selectively inhibit A2A receptors thereby modulating the indirect basal ganglia pathway and influencing neuronal activity involved in motor control Tozadenant exerts its biological activity primarily through selective A2A receptor blockade In animal models tozadenant demonstrates enhancement of motor neuron function Human studies using perfusion MRI indicate that administration of tozadenant decreases regional cerebral blood flow particularly in bilateral thalamic areas Based on these pharmacological properties tozadenant holds research potential in investigating Parkinson s disease and movement disorders associated with basal ganglia dysfunction
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