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Cayman Chemical TP-238hydrochlorIde 10mg
Supplier: Cayman Chemical 2725410 MG
A chemical probe for CECR2 and BPTF bromodomains; has on-target biochemical activity with CECR2 at 10-30 nM and with BPTF at 100-350 nM; selective for the CECR2 and BPTF bromodomains over BRD9 (IC50 = 1.4 µM), as well as over a panel of 338 kinases at 1 µM; binds to CECR2 and BPTF in ITC (KDs =10 and 120 nM, respectively) and AlphaScreen assays (IC50s - 30 and 350 nM, respectively)
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