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Medchemexpress LLC TP-5801 (TFA) | 99.6% | 641.48 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY147316A100MG

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TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor with an IC50 of 1.40 nM, demonstrating anti-tumor activity. It inhibits TNK1-driven, BCR-ABL-driven, and IL-3-driven Ba/F3 cell growth, and TNK1-dependent L540 cell growth.

  • Orally active
  • Potent TNK1 inhibitor (IC50=1.40 nM)
  • Demonstrates anti-tumor activity
  • Inhibits growth of various cell lines (Ba/F3 and L540) relevant to TNK1-driven processes
  • Shows efficacy in animal models, prolonging lifespan and inhibiting localized tumor growth without signs of toxicity

Catalog No. 50-003-60385


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