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Medchemexpress LLC TP-5801 (TFA) | 99.6% | 641.48 | 25 MG

Supplier: Medchemexpress LLC 25MGHY147316A
TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor with an IC50 of 1.40 nM. This compound demonstrates anti-tumor activity and is suitable for various research applications.
- Inhibits TNK1-driven, BCR-ABL-driven, and IL-3-driven Ba/F3 cell growth.
- Inhibits TNK1-dependent L540 cell growth at low nM levels.
- Shows efficacy in mouse survival models, significantly prolonging lifespan.
- Inhibits localized tumor growth in mouse xenograft models.
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