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Medchemexpress LLC TP-5801 (TFA) | 99.6% | 641.48 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY147316A50MG

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TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor with an IC50 of 1.40 nM. It demonstrates significant anti-tumor activity both in vitro and in vivo. This compound is stable under recommended storage conditions and is for research use only.

  • Inhibits TNK1-driven, BCR-ABL-driven, and IL-3-driven Ba/F3 cell growth
  • Inhibits TNK1-dependent L540 cell growth at low nanomolar levels
  • Shows efficacy in mouse survival models with no observed toxicity
  • Reduces localized tumor growth and phospho-STAT3 in xenograft models

Catalog No. 50-003-61417


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