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Cayman Chemical TPMPAhydrate 10mg
SDP

Supplier:  Cayman Chemical 2430210 MG

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A selective GABAA-ρ1 (ρ1 GABAC) receptor antagonist (Kbs = 2 and 16 μM for GABAA-ρ1 over GABAA-ρ2, respectively); blocks the inhibitory effect of 3-APMPA on EPSCs in rat hippocampal slices (EC50 = 490 μM); increases light sensitivity and the maximal response of rat retinal ganglion cells without altering their dynamic range (100 μM); increases waking from 45 to 62% compared to vehicle control and decreases slow-wave and REM by 11 and 5.4%, respectively, in rats (50 μg, i.c.v.)

Catalog No. 50-293-6106


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