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Cayman Chemical TPT-260hydrochlorIde 10mg
Supplier: Cayman Chemical 1607910 MG
A thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~5 µM); dose-dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of pathogenic APP in cultured hippocampal neurons
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