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Cayman Chemical TR-FRET asy Buffer AddItIve 1g
Supplier: Cayman Chemical 6005041 G
An ionizable cationic lipid has been used in the generation of LNPs for the delivery of mRNA in vivo LNPs containing 119-23 and encapsulating an mRNA reporter show greater intramuscular transfection efficacy compared to LNPs containing SM-102 or DLin-MC3-DMA in mice 119-23-containing LNPs accumulate in mouse hepatic and splenic immune cells to a greater extent than SM-102-containing LNPs LNPs containing 119-23 and encapsulating mRNA encoding hEPO increase serum hEPO levels in mice
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