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ABclonal Technology TRAF4 Rabbit mAb
SDP

Catalog No. 5000007056
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This gene encodes a member of the TNF receptor associated factor (TRAF) family TRAF proteins are associated with and mediate signal transduction from members of the TNF receptor superfamily The encoded protein has been shown to interact with neurotrophin receptor p75 (NTR NTSR1) and negatively regulate NTR induced cell death and NF-kappa B activation This protein has been found to bind to p47phox a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase This protein thus is thought to be involved in the oxidative activation of MAPK8 JNK Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

Catalog No. 50-000-07056 Supplier ABclonal Technology Supplier No. A22472100UL
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This gene encodes a member of the TNF receptor associated factor (TRAF) family TRAF proteins are associated with and mediate signal transduction from members of the TNF receptor superfamily The encoded protein has been shown to interact with neurotrophin receptor p75 (NTR NTSR1) and negatively regulate NTR induced cell death and NF-kappa B activation This protein has been found to bind to p47phox a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase This protein thus is thought to be involved in the oxidative activation of MAPK8 JNK Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

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