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AdipoGen anti-TRAIL-R1 (human), mAb (HS101) (FITC) (100 tests)
SDP

Supplier:  AdipoGen AG20B0022FT100

Encompass_Preferred

Monoclonal Antibody. Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4. Isotype: Mouse IgG1. Clone: HS101. Applications: FACS, ICC. Liquid. In PBS containing 0.02% sodium azide. TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

Catalog No. 50-205-2920


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