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Enzo Life Sciences Tranilast (10mg). CAS: 53902-12-8
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Supplier:  Enzo Life Sciences ALX550409M010

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Anti-inflammatory and anti-angiogenic agent. Inhibits VEGF-induced angiogenesis in vivo . Inhibits proliferation and tube formation of human endothelial cells in vitro. Also inhibits smooth muscle cell proliferation and prevents post-angiplasty retsenosis.Synthetic compound with structural similarity to the tryptophan (Trp) catabolites kynurenines. Tranilast ameliorates the disease severity in animal models of multiple sclerosis, in part, by inducing T cell tolerance. Trp degradation is an important mechanism in the maintenance of T cell tolerance in a variety of disease models and is mediated by the rate limiting enzyme indoleamine 2,3-dioxygenase (IDO). Alternative name: N-(3',4'-Dimethoxycinnamoyl)anthranilic acid, 3,4-DAA. Purity: ≥95% (HPLC). Appearance: Off-white to yellow solid. Solubility: Soluble in DMSO. Long Term Storage: -20°C.

Catalog No. 50-200-9554


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