trans-1-(Boc-amino)-4-(hydroxymethyl)cyclohexane, 97%

Description

CAS: 239074-29-4 | C12H23NO3 | 229.32 g/mol

trans-1-(Boc-amino)-4-(hydroxymethyl)cyclohexane is used to prepare C-2 hydroxyethyl imidazopyrrolo pyridines as JAK1 inhibitors. It is also used to prepare Mer kinase inhibitors for treatment of pediatric acute lymphoblastic leukemia.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
trans-1-(Boc-amino)-4-(hydroxymethyl)cyclohexane is used to prepare C-2 hydroxyethyl imidazopyrrolo pyridines as JAK1 inhibitors. It is also used to prepare Mer kinase inhibitors for treatment of pediatric acute lymphoblastic leukemia.

Solubility
Slightly Soluble (4.4 g/L) (25°C).

Notes
Store in cool, dry place in tightly closed container. Keep container tightly closed. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 239074-29-4
• Molecular Formula: C12H23NO3
• Molecular Weight (g/mol): 229.32
• MDL Number: MFCD03844605
• InChI Key: SGNKPJPMWHKOJO-UHFFFAOYSA-N
• Synonym: tert-butyl trans-4-hydroxymethyl cyclohexylcarbamate, tert-butyl trans-4-hydroxymethyl cyclohexyl carbamate, tert-butyl cis-4-hydroxymethyl cyclohexyl carbamate, tert-butyl n-4-hydroxymethyl cyclohexyl carbamate, trans-n-4-hydroxymethyl cyclohexyl carbamic acid tert-butyl ester, tert-butyl 4-hydroxymethyl cyclohexyl carbamate, tert-butyl trans-4-hydroxymethyl-cyclohexylcarbamate, trans-tert-butyl 4-hydroxymethyl cyclohexyl carbamate, tert-butyl cis-4-hydroxymethyl cyclohexylcarbamate
• PubChem CID: 10513598
• IUPAC Name: tert-butyl N-[4-(hydroxymethyl)cyclohexyl]carbamate
• SMILES: CC(C)(C)OC(=O)NC1CCC(CC1)CO

• Solubility Information: Slightly Soluble (4.4g/L) (25°C).
• Quantity: 1 g
• Formula Weight: 229.31
• Percent Purity: 97%
• Physical Form: Solid
• Chemical Name or Material: trans-1-(Boc-amino)-4-(hydroxymethyl)cyclohexane

Safety and Handling

TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only