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Medchemexpress LLC Trans-ccc_R08 | 2413192-49-9 | 99.7% | 414.84 | 25 MG
Supplier: Medchemexpress LLC 25MGHY148560A
Trans-ccc_R08 (Compound 1-B) is a cccDNA inhibitor with anti-HBV activity. It has an IC50 of 0.14 μM for HBeAg and an IC50 of 0.08 μM for HBsAg in in vitro assays. This compound inhibits covalently closed circular DNA (cccDNA) and is applicable to research related to hepatitis B virus infection.
- Inhibits HBeAg production in HepDES19 cells with an IC50 of 0.14 μM.
- Inhibits HBsAg production in cryopreserved primary hepatocytes with an IC50 of 0.08 μM.
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